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Search Results for " DNA synthesis "

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417

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85

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42

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カタログ番号 製品名 別名 ターゲット
T36757 DMT-dU-CE Phosphoramidite DNA/RNA Synthesis
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.
T12019 Methylproamine Others
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
T8873 Bractoppin Others , DNA/RNA Synthesis
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...
T14522 Beaucage reagent DNA/RNA Synthesis
Beaucage reagent, which is found to be effective in causing DNA cleavage.
TP1115 L-Asparaginase L-​ASNase Others
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a...
T36756 DMT-dG(ib) Phosphoramidite DNA/RNA Synthesis
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
T6801 CeMMEC13 Carboxypeptidase , DNA/RNA Synthesis
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
T1154 Rifaximin DNA/RNA Synthesis , Antibacterial , Antibiotic
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting...
T4517 L189 DNA , DNA/RNA Synthesis
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
T15611 JH-RE-06 DNA/RNA Synthesis
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...
T8003 Methotrexate disodium Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
T0164 Oxaliplatin L-OHP DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...
T3103 L67 DNA Ligase Inhibitor DNA , DNA/RNA Synthesis
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T8747 Levofloxacin hydrochloride DNA gyrase , Topoisomerase
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh...
T8354 Triazavirin Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T3279 Silver sulfadiazine Silvadene,Dermazin,Flamazine DNA/RNA Synthesis , Antibacterial , Antibiotic
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.
T2037 TH588 DNA/RNA Synthesis , MTH1
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.
T8955 PCNA-I1 Others
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.
T8886 NITD-2 DNA/RNA Synthesis
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu...
T2100 CX-5461 DNA/RNA Synthesis
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.
T36687 Ac-rC Phosphoramidite Nucleoside Antimetabolite/Analog
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
T2410 Nedaplatin NSC 375101D DNA/RNA Synthesis
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand...
T40168 DHODH-IN-16 Dehydrogenase
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
T8648 6-AZATHYMINE Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis , Antibacterial
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic...
T15235 Enocitabine Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ...
T15793 Lurbinectedin PM01183 Others
Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.
T14501 BAY-2402234 Dehydrogenase , DNA/RNA Synthesis
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.
T7747 Datelliptium chloride hydrochloride DNA/RNA Synthesis
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
T1058 Carboplatin NSC 241240,CBDCA,JM-8 DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
T5017 Nimustine Hydrochloride Nidran hydrochloride Apoptosis , Others , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.
T16703 Quarfloxin CX-3543 DNA/RNA Synthesis
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...
T1233 Oxolinic acid Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
T9103 BVDV-IN-1 DNA/RNA Synthesis
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to...
T11020 DHODH-IN-11 Dehydrogenase , DNA/RNA Synthesis
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
T40661 ML-60218 DNA/RNA Synthesis
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.
T4345 CeMMEC1 CeMMEC1 HCl Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
T1349 5-Fluorouridine Others , DNA/RNA Synthesis
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...
T9121 AG-636 Dehydrogenase , DNA/RNA Synthesis
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
T13659 DMTr-LNA-5MeU-3-CED-phosphoramidite Nucleoside Antimetabolite/Analog
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
T21463 Temozolomide Acid TMZA Others
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt...
T12438 PfDHODH-IN-1 Dehydrogenase , Parasite
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
T0220 Foscarnet sodium Phosphonoformate Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T11546 HDHODH-IN-1 Dehydrogenase
T2069L TH287 hydrochloride DNA/RNA Synthesis , MTH1
TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
T1724 SCR7 pyrazine SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T6357 (S)-crizotinib ent-crizotinib Apoptosis , DNA/RNA Synthesis , MTH1
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
T5363 Tempo 2,2,6,6-Tetramethylpiperidinooxy Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T5413 ML216 CID-49852229 DNA/RNA Synthesis
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM).
T40192 DGTP 2'-Deoxyguanosine-5'-triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

Compounds

DMT-dU-CE Phosphoramidite
T36757
Synonym:
Target: DNA/RNA Synthesis
Methylproamine
T12019
Synonym:
Target: Others
Bractoppin
T8873
Synonym:
Target: Others, DNA/RNA Synthesis
Beaucage reagent
T14522
Synonym:
Target: DNA/RNA Synthesis
L-Asparaginase
TP1115
Synonym: L-​ASNase
Target: Others
DMT-dG(ib) Phosphoramidite
T36756
Synonym:
Target: DNA/RNA Synthesis
CeMMEC13
T6801
Synonym:
Target: Carboxypeptidase, DNA/RNA Synthesis
Rifaximin
T1154
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
L189
T4517
Synonym:
Target: DNA, DNA/RNA Synthesis
JH-RE-06
T15611
Synonym:
Target: DNA/RNA Synthesis
Methotrexate disodium
T8003
Synonym:
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate
Oxaliplatin
T0164
Synonym: L-OHP
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
L67
T3103
Synonym: DNA Ligase Inhibitor
Target: DNA, DNA/RNA Synthesis
Levofloxacin hydrochloride
T8747
Synonym:
Target: DNA gyrase, Topoisomerase
Triazavirin
T8354
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis
Silver sulfadiazine
T3279
Synonym: Silvadene,Dermazin,Flamazine
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
TH588
T2037
Synonym:
Target: DNA/RNA Synthesis, MTH1
PCNA-I1
T8955
Synonym:
Target: Others
NITD-2
T8886
Synonym:
Target: DNA/RNA Synthesis
CX-5461
T2100
Synonym:
Target: DNA/RNA Synthesis
Ac-rC Phosphoramidite
T36687
Synonym:
Target: Nucleoside Antimetabolite/Analog
BMH-21
T1767
Synonym: BMH21
Target: DNA/RNA Synthesis
Nedaplatin
T2410
Synonym: NSC 375101D
Target: DNA/RNA Synthesis
DHODH-IN-16
T40168
Synonym:
Target: Dehydrogenase
6-AZATHYMINE
T8648
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial
Enocitabine
T15235
Synonym:
Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis
Lurbinectedin
T15793
Synonym: PM01183
Target: Others
BAY-2402234
T14501
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
Datelliptium chloride hydrochloride
T7747
Synonym:
Target: DNA/RNA Synthesis
Carboplatin
T1058
Synonym: NSC 241240,CBDCA,JM-8
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
Nimustine Hydrochloride
T5017
Synonym: Nidran hydrochloride
Target: Apoptosis, Others, DNA Alkylator/Crosslinker, DNA/RNA Synthesis
Quarfloxin
T16703
Synonym: CX-3543
Target: DNA/RNA Synthesis
Oxolinic acid
T1233
Synonym: Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox
Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic
BVDV-IN-1
T9103
Synonym:
Target: DNA/RNA Synthesis
DHODH-IN-11
T11020
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
ML-60218
T40661
Synonym:
Target: DNA/RNA Synthesis
CeMMEC1
T4345
Synonym: CeMMEC1 HCl
Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis
5-Fluorouridine
T1349
Synonym:
Target: Others, DNA/RNA Synthesis
AG-636
T9121
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
DMTr-LNA-5MeU-3-CED-phosphoramidite
T13659
Synonym:
Target: Nucleoside Antimetabolite/Analog
Temozolomide Acid
T21463
Synonym: TMZA
Target: Others
PfDHODH-IN-1
T12438
Synonym:
Target: Dehydrogenase, Parasite
Foscarnet sodium
T0220
Synonym: Phosphonoformate
Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis
hDHODH-IN-1
T11546
Synonym:
Target: Dehydrogenase
TH287 hydrochloride
T2069L
Synonym:
Target: DNA/RNA Synthesis, MTH1
SCR7 pyrazine
T1724
Synonym: SCR7
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
(S)-crizotinib
T6357
Synonym: ent-crizotinib
Target: Apoptosis, DNA/RNA Synthesis, MTH1
Tempo
T5363
Synonym: 2,2,6,6-Tetramethylpiperidinooxy
Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism
ML216
T5413
Synonym: CID-49852229
Target: DNA/RNA Synthesis
dGTP
T40192
Synonym: 2'-Deoxyguanosine-5'-triphosphate
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
1 2 3 4 5 6 7 8 9
カタログ番号 製品名 別名 ターゲット
T21498 Phleomycin DNA/RNA Synthesis , Antibacterial , Antibiotic
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
T7520 Deoxycytidine triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T13969 Xanthopterin (hydrate) Others , DNA/RNA Synthesis
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.
T40179 Sodium Camptothecin DNA/RNA Synthesis
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...
T37101 1-Hydroxyanthraquinone DNA/RNA Synthesis
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
T2S1635 3-Isomangostin MTH1
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...
T1068 Dithranol 1,8,9-trihydroxyanthracene,cignoline,Anthralin Others , DNA/RNA Synthesis
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
T6S0139 Neobavaisoflavone Apoptosis , DNA/RNA Synthesis
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T5901 3-Hydroxy-2-methylpyridine Others
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
TN2132 Quinizarin 1,4-Dihydroxyanthraquinone Others , DNA/RNA Synthesis , Antifungal
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product
TQ0184 Chebulinic acid ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T35455 N-Nitrosodiethylamine Diethylnitrosamine,NDEA DNA/RNA Synthesis
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...
T6S0232 Eriodictyol Huazhongilexone Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3....
T0064 Adenine Vitamin B4,6-Aminopurine DNA/RNA Synthesis , Endogenous Metabolite , AChR
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic...
TWP2911 Thymidine 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin Others , DNA/RNA Synthesis , Endogenous Metabolite
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
T16674 Pseudouridine Endogenous Metabolite
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
TN1637 Eurycomalactone Anti-infection , NF-κB
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in...
T13229 Tunicamycin Influenza Virus , Antibacterial , Antibiotic , Antifungal
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity...
T6567 Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin Topoisomerase , Antibacterial , Antibiotic
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
T2998 Dihydromyricetin Ampelopsin,Ampeloptin Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy...
T4593 ISOPIMPINELLIN 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen Antiviral , DNA/RNA Synthesis , Parasite
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T20945 2,4-D Hedonal,Macondray,2,4-D acid,Chloroxone DNA/RNA Synthesis
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti...
T6225 Adenine hydrochloride Adenine HCl,6-Aminopurine hydrochloride DNA/RNA Synthesis , Endogenous Metabolite
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
T13791 N2-methylguanine DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.
T0974 Novobiocin Sodium Albamycinsodium,Cathomycin,Albamycin Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T6369 Adenine hemisulfate Diadenine sulphate,Adenine sulfate,Adeninsulfat DNA/RNA Synthesis , Endogenous Metabolite
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
T1507 Streptozocin STZ,Streptozotocin,NSC-85998,U 9889 DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th...
T6116 Bleomycin Sulfate Blenoxane,NSC125066 DNA/RNA Synthesis , Antibiotic
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
T6758 Anisomycin Flagecidin,NSC 76712,Wuningmeisu C Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T7004 Tubercidin Sparsomycin A,7-Deazaadenosine Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
TN1097 β-Boswellic acid Beta-boswellic acid Lipoxygenase , DNA/RNA Synthesis
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.
T3343 5-methoxyflavone 5-methoxy-2-phenylchromen-4-one DNA/RNA Synthesis
5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
T7174 Urolithin A Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
T38427 DUTP trisodium 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate DNA/RNA Synthesis
dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
T7094 Levomefolic Acid 5-MTHF Reactive Oxygen Species , Endogenous Metabolite
Levomefolic Acid (5-MTHF) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used a...
T0062 Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin DNA/RNA Synthesis , Endogenous Metabolite
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.
T40426 Cytidine 5'-diphosphate trisodium salt CDP Others
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp...
T1272 Cytarabine Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
T6194 Fidaxomicin Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T9086 Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt DNA/RNA Synthesis
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ...
T4706 Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction...
T2A2537 Guanine Pearl essence,Mearlmaid,2-Aminohypoxanthine Others , DNA/RNA Synthesis , Endogenous Metabolite
Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T1511 Daunorubicin hydrochloride Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T3376 Cynaroside Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside Others , Influenza Virus , DNA/RNA Synthesis
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
T1703 SN-38 NK012,SN 38 DNA/RNA Synthesis , Topoisomerase , Autophagy
SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 has antitumor activity and induces autophagy.
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天然物製品

Phleomycin
T21498
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Deoxycytidine triphosphate
T7520
Synonym:
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite
Xanthopterin (hydrate)
T13969
Synonym:
Target: Others, DNA/RNA Synthesis
Sodium Camptothecin
T40179
Synonym:
Target: DNA/RNA Synthesis
1-Hydroxyanthraquinone
T37101
Synonym:
Target: DNA/RNA Synthesis
3-Isomangostin
T2S1635
Synonym:
Target: MTH1
Dithranol
T1068
Synonym: 1,8,9-trihydroxyanthracene,cignoline,Anthralin
Target: Others, DNA/RNA Synthesis
Neobavaisoflavone
T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
Euscaphic acid
TN1134
Synonym:
Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor
3-Hydroxy-2-methylpyridine
T5901
Synonym:
Target: Others
5-Methylcytosine
T5270
Synonym:
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
Quinizarin
TN2132
Synonym: 1,4-Dihydroxyanthraquinone
Target: Others, DNA/RNA Synthesis, Antifungal
Chebulinic acid
TQ0184
Synonym:
Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad
N-Nitrosodiethylamine
T35455
Synonym: Diethylnitrosamine,NDEA
Target: DNA/RNA Synthesis
Eriodictyol
T6S0232
Synonym: Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
Adenine
T0064
Synonym: Vitamin B4,6-Aminopurine
Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR
Thymidine
TWP2911
Synonym: 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
Pseudouridine
T16674
Synonym:
Target: Endogenous Metabolite
Eurycomalactone
TN1637
Synonym:
Target: Anti-infection, NF-κB
Tunicamycin
T13229
Synonym:
Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal
Levofloxacin
T6567
Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin
Target: Topoisomerase, Antibacterial, Antibiotic
Dihydromyricetin
T2998
Synonym: Ampelopsin,Ampeloptin
Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy
ISOPIMPINELLIN
T4593
Synonym: 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen
Target: Antiviral, DNA/RNA Synthesis, Parasite
Aplidine
T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
2,4-D
T20945
Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone
Target: DNA/RNA Synthesis
Adenine hydrochloride
T6225
Synonym: Adenine HCl,6-Aminopurine hydrochloride
Target: DNA/RNA Synthesis, Endogenous Metabolite
N2-methylguanine
T13791
Synonym:
Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial
Novobiocin Sodium
T0974
Synonym: Albamycinsodium,Cathomycin,Albamycin
Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy
Adenine hemisulfate
T6369
Synonym: Diadenine sulphate,Adenine sulfate,Adeninsulfat
Target: DNA/RNA Synthesis, Endogenous Metabolite
Streptozocin
T1507
Synonym: STZ,Streptozotocin,NSC-85998,U 9889
Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy
Bleomycin Sulfate
T6116
Synonym: Blenoxane,NSC125066
Target: DNA/RNA Synthesis, Antibiotic
Anisomycin
T6758
Synonym: Flagecidin,NSC 76712,Wuningmeisu C
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK
Tubercidin
T7004
Synonym: Sparsomycin A,7-Deazaadenosine
Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic
β-Boswellic acid
TN1097
Synonym: Beta-boswellic acid
Target: Lipoxygenase, DNA/RNA Synthesis
5-methoxyflavone
T3343
Synonym: 5-methoxy-2-phenylchromen-4-one
Target: DNA/RNA Synthesis
Urolithin A
T7174
Synonym:
Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite
dUTP trisodium
T38427
Synonym: 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate
Target: DNA/RNA Synthesis
Levomefolic Acid
T7094
Synonym: 5-MTHF
Target: Reactive Oxygen Species, Endogenous Metabolite
Folic acid
T0062
Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin
Target: DNA/RNA Synthesis, Endogenous Metabolite
Cytidine 5'-diphosphate trisodium salt
T40426
Synonym: CDP
Target: Others
Cytarabine
T1272
Synonym: Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV
Fidaxomicin
T6194
Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Deoxythymidine-5'-triphosphate trisodium
T9086
Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt
Target: DNA/RNA Synthesis
Uridine-5'-diphosphate disodium salt
T4706
Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd
Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor
Guanine
T2A2537
Synonym: Pearl essence,Mearlmaid,2-Aminohypoxanthine
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Daunorubicin hydrochloride
T1511
Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin
Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Cynaroside
T3376
Synonym: Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside
Target: Others, Influenza Virus, DNA/RNA Synthesis
SN-38
T1703
Synonym: NK012,SN 38
Target: DNA/RNA Synthesis, Topoisomerase, Autophagy

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00608 Dihydrofolate reductase Protein, E. coli, Recombinant (His) E. coli E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-00360 DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant Cenarchaeum symbiosum E. coli
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicativ...
TMPH-00523 DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc) Escherichia phage RB69 E. coli
Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreadin...
TMPH-03535 Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed...
TMPH-01224 Dihydrofolate reductase Protein, Human, Recombinant (His) Human E. coli
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds...
TMPH-01584 KRT7 Protein, Human, Recombinant (His & SUMO) Human E. coli
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
TMPH-00028 Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) AAV-2 E. coli
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a...
TMPH-03581 Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) Staphylococcus epidermidis E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed ...
TMPH-00529 UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His) Enterobacteria phage T4 E. coli
Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA.
TMPY-02543 PCNA Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its ...
TMPH-00427 DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant Colwellia psychrerythraea E. coli
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers...
TMPH-00578 NrdD Protein, E. coli, Recombinant (His) E. coli E. coli
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag....
TMPY-02527 P53R2 Protein, Human, Recombinant (His) Human E. coli
Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase...
TMPH-00531 SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO) Enterobacteria phage T7 E. coli
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance...
TMPH-00426 DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) Colwellia psychrerythraea E. coli
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers...
TMPH-00532 SSB Protein, Enterobacteria phage T7, Recombinant Enterobacteria phage T7 P. pastoris (Yeast)
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance...
TMPJ-00792 DNA PolymeraseBeta Protein, Human, Recombinant (His) Human E. coli
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p...
TMPK-01386 TK1 Potein, Canine, Recombinant (His) Canine E. coli
Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phas...
TMPH-02568 CTGF/CCN2 Protein, Mouse, Recombinant (GST) Mouse E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ...
TMPH-01270 TRAIP Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin ligase required to protect genome stability in response to replication stress. Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethe...
TMPJ-00937 RRM2 Protein, Human, Recombinant (His) Human HEK293 Cells
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. S...
TMPJ-00725 HGPRT Protein, Human, Recombinant (His) Human E. coli
Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed pur...
TMPJ-01408 HDGFRP3 Protein, Human, Recombinant (His) Human HEK293 Cells
Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 ...
TMPH-01237 POLQ Protein, Human, Recombinant (E. coli, His) Human E. coli
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw...
TMPH-01238 POLQ Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw...
TMPY-05055 GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His) Human HEK293 Cells
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres...
TMPH-03452 NDPK Protein, S. cerevisiae, Recombinant (His) Saccharomyces cerevisiae P. pastoris (Yeast)
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPH-01069 CTGF/CCN2 Protein, Human, Recombinant (His) Human E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ...
TMPH-03451 NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) Saccharomyces cerevisiae E. coli
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPJ-01131 UBE2V2 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N....
TMPJ-00905 DTYMK Protein, Human, Recombinant (His) Human HEK293 Cells
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis...
TMPJ-00718 AIF Protein, Human, Recombinant (His) Human E. coli
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is t...
TMPJ-00769 TK1 Protein, Human, Recombinant (His) Human HEK293 Cells
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identifi...
TMPJ-01100 UBE2V1 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inact...
TMPJ-01118 GNMT Protein, Human, Recombinant (His) Human E. coli
Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation b...
TMPY-03287 RRM1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPY-02840 Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cl...
TMPY-03655 GADD45G Protein, Human, Recombinant Human E. coli
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPY-02402 WTAP Protein, Human, Recombinant (GST) Human E. coli
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif...
TMPY-00924 SMAC Protein, Human, Recombinant (His) Human E. coli
Apoptosis is an essential processes required for normal development and homeostasis of all metazoan organisms. Second Mitochondria-Derived Activator of Caspases (Smac) or Direct IAP Binding Protein with low isoelectric p...
TMPY-02198 ILKAP Protein, Human, Recombinant (His) Human HEK293 Cells
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve...
TMPH-01689 PLD6 Protein, Human, Recombinant (His) Human E. coli
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the...
Dihydrofolate reductase Protein, E. coli, Recombinant (His)
TMPH-00608
Species: E. coli
Expression System: E. coli
DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant
TMPH-00360
Species: Cenarchaeum symbiosum
Expression System: E. coli
DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)
TMPH-00523
Species: Escherichia phage RB69
Expression System: E. coli
Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
TMPH-03535
Species: Staphylococcus aureus
Expression System: E. coli
Dihydrofolate reductase Protein, Human, Recombinant (His)
TMPH-01224
Species: Human
Expression System: E. coli
KRT7 Protein, Human, Recombinant (His & SUMO)
TMPH-01584
Species: Human
Expression System: E. coli
Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)
TMPH-00028
Species: AAV-2
Expression System: E. coli
Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
TMPH-03581
Species: Staphylococcus epidermidis
Expression System: E. coli
UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His)
TMPH-00529
Species: Enterobacteria phage T4
Expression System: E. coli
PCNA Protein, Human, Recombinant (His)
TMPY-02543
Species: Human
Expression System: Baculovirus Insect Cells
DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant
TMPH-00427
Species: Colwellia psychrerythraea
Expression System: E. coli
NrdD Protein, E. coli, Recombinant (His)
TMPH-00578
Species: E. coli
Expression System: E. coli
p53R2 Protein, Human, Recombinant (His)
TMPY-02527
Species: Human
Expression System: E. coli
SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO)
TMPH-00531
Species: Enterobacteria phage T7
Expression System: E. coli
DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)
TMPH-00426
Species: Colwellia psychrerythraea
Expression System: E. coli
SSB Protein, Enterobacteria phage T7, Recombinant
TMPH-00532
Species: Enterobacteria phage T7
Expression System: P. pastoris (Yeast)
DNA PolymeraseBeta Protein, Human, Recombinant (His)
TMPJ-00792
Species: Human
Expression System: E. coli
TK1 Potein, Canine, Recombinant (His)
TMPK-01386
Species: Canine
Expression System: E. coli
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
TMPH-02568
Species: Mouse
Expression System: E. coli
TRAIP Protein, Human, Recombinant (His)
TMPH-01270
Species: Human
Expression System: E. coli
RRM2 Protein, Human, Recombinant (His)
TMPJ-00937
Species: Human
Expression System: HEK293 Cells
HGPRT Protein, Human, Recombinant (His)
TMPJ-00725
Species: Human
Expression System: E. coli
HDGFRP3 Protein, Human, Recombinant (His)
TMPJ-01408
Species: Human
Expression System: HEK293 Cells
POLQ Protein, Human, Recombinant (E. coli, His)
TMPH-01237
Species: Human
Expression System: E. coli
POLQ Protein, Human, Recombinant (His)
TMPH-01238
Species: Human
Expression System: Baculovirus Insect Cells
GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)
TMPY-05055
Species: Human
Expression System: HEK293 Cells
NDPK Protein, S. cerevisiae, Recombinant (His)
TMPH-03452
Species: Saccharomyces cerevisiae
Expression System: P. pastoris (Yeast)
CTGF/CCN2 Protein, Human, Recombinant (His)
TMPH-01069
Species: Human
Expression System: E. coli
NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)
TMPH-03451
Species: Saccharomyces cerevisiae
Expression System: E. coli
UBE2V2 Protein, Human, Recombinant (His)
TMPJ-01131
Species: Human
Expression System: E. coli
DTYMK Protein, Human, Recombinant (His)
TMPJ-00905
Species: Human
Expression System: HEK293 Cells
AIF Protein, Human, Recombinant (His)
TMPJ-00718
Species: Human
Expression System: E. coli
TK1 Protein, Human, Recombinant (His)
TMPJ-00769
Species: Human
Expression System: HEK293 Cells
UBE2V1 Protein, Human, Recombinant (His)
TMPJ-01100
Species: Human
Expression System: E. coli
GNMT Protein, Human, Recombinant (His)
TMPJ-01118
Species: Human
Expression System: E. coli
RRM1 Protein, Human, Recombinant (His & GST)
TMPY-03287
Species: Human
Expression System: Baculovirus Insect Cells
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
TMPY-02840
Species: Human
Expression System: Baculovirus Insect Cells
GADD45G Protein, Human, Recombinant
TMPY-03655
Species: Human
Expression System: E. coli
WTAP Protein, Human, Recombinant (GST)
TMPY-02402
Species: Human
Expression System: E. coli
SMAC Protein, Human, Recombinant (His)
TMPY-00924
Species: Human
Expression System: E. coli
ILKAP Protein, Human, Recombinant (His)
TMPY-02198
Species: Human
Expression System: HEK293 Cells
PLD6 Protein, Human, Recombinant (His)
TMPH-01689
Species: Human
Expression System: E. coli
カタログ番号 製品名
L5500 Toxic Compound Library

262 compounds
A unique collection of 262 toxic substances for high throughput screening (HTS) and high content screening (HCS);
L8100 Cell Cycle Compound Library

677 compounds
A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);